Yorke autolytic reaction[yōrk]

Type:Term

Definitions
1. a test for paroxysmal hemoglobinuria; serum is placed in an ice chest and kept at 0°C for 5–7 minutes, then in an incubator at 37°C with erythrocytes for 1 hour, at which time, if the reaction is positive, hemolysis occurs; if the serum is kept at 1°C for an hour and then placed in the incubator with erythrocytes there is little hemolysis.

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