yolk sac

Type:Term

Definitions
1. in vertebrates with telolecithal eggs, the highly vascular layer of splanchnopleure surrounding the yolk of an embryo;
2. in humans and other mammals, the sac of extraembryonic membrane that is located ventral to the embryonic disk and, after formation of the gut tube, is connected to the midgut; by the second month of development, this connection has become the narrow yolk stalk; the yolk sac is the first hematopoietic organ of the embryo, and its vitelline circulation plays an important role in the early embryonic circulation; the sac is also the site of origin of the primordial germ cells.

Synonyms
umbilical vesicle , vesicula umbilicalis , vitelline sac

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