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Musculoskeletal Drugs

Prescription drugs and medicines relating to the muscles and the bones of the body. Studies in this area include: aging, bone density, bone fractures, chronic back pain, hip replacement, osteoarthritis, osteoporosis, rheumatoid arthritis, spinal cord injuries, and others.

The list of FDA approved drugs for musculoskeletal appears below. Click any link to view the full drug information.

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Number Of Musculoskeletal Drugs: 91

Actemra (ocilizumab)
For the treatment of Polyarticular Juvenile Idiopathic Arthritis
Actemra (tocilizumab)
For the treatment of rheumatoid arthritis
Actemra (tocilizumab)
For the treatment of systemic juvenile idiopathic arthritis
Activella (Estradiol/Norethindrone Acetate) Tablets
Combination hormone replacement therapy for the prevention of osteoporosis and other symptoms associated w/postmenopause
Treatment for Paget's Disease
Aldurazyme (laronidase)
For the treatment of Mucopolysaccharidosis I (MPS I) in subjects aged 5 to 65
Transdermal patch for the prevention of postmenopausal osteoporosis and treatment of vasomotor menopausal symptoms
Ampyra (dalfampridine)
For the improvement of walking in patients with multiple sclerosis
Amrix (cyclobenzaprine hydrochloride extended release)
For the treatment of muscle spasm associated with acute, painful musculoskeletal conditions
Treatment for arthritis
Atracurium Besylate Injection
Generic equivalent of Tracrium
Aubagio (teriflunomide)
For the treatment of multiple sclerosis
Avinza (morphine sulfate)
Extended release capsule for the relief of pain requiring continuous, around-the-clock therapy
Boniva (ibandronate)
For the treatment and prevention of osteoporosis
Botox (onabotulinumtoxinA)
For the treatment of upper limb spasticity
Cimzia (certolizumab pegol)
For the treatment of rheumatoid arthritis
Colcrys (colchicine)
For gout flares and familial Mediterranean fever
Duavee (conjugated estrogens/bazedoxifene)
For the treatment of vasomotor symptoms associated with menopause and postmenopausal osteoporosis
Duexis (ibuprofen and famotidine)
For the relief of rheumatoid arthritis and osteoarthritis and prevention of gastric ulcers
Elelyso (taliglucerase alfa)
For the treatment of Gaucher disease
Estradiol tablets
Generic equivalent of Estrace
Estratab (.3 mg )
Treatment for the prevention of osteoporosis
Generic equivalent of Lodine
Generic equivalent of Lodine 500 mg tablets
Evista (raloxifene hydrochloride)
Osteoporosis treatment
Evista (raloxifene hydrochloride)
Treatment for the prevention of osteoporosis
Evista (raloxifene hydrochloride)
For the treatment/prevention of osteoporosis and reduction of breast cancer risk in postmenopausal women
Exondys 51 (eteplirsen)
For the treatment of Duchenne muscular dystrophy with mutated DMD gene amenable to exon 51 skipping
Extavia (Interferon beta-l b)
For the treatment of relapsing multiple sclerosis
Femhrt Tablets
Norethindrone acetate (1mg) and ethinyl estradiol tablets (5mcg)
Forteo (teriparatide)
For the treatment of Osteoporosis in postmenopausal women and men who are at high risk for a fracture.
Fosamax (alendronate sodium)
Treatment for osteoporosis in women after menopause and Paget's Disease of Bone
Genotropin (somatropin) injection
For the treatment of growth failure in children who were born small for gestational age (SGA)
Gilenya (fingolimod)
For the treatment of relapsing multiple sclerosis
Ilaris (canakinumab)
For the treatment of Systemic Juvenile Idiopathic Arthritis
Treatment for chronic moderate to severe pain
Generic equivalent or Oruvail
Injectable therapy for the treatment of rheumatoid arthritis
Krystexxa (pegloticase)
For the treatment of chronic gout (hyperuricemia)
Lemtrada (alemtuzumab)
For the treatment of relapsing multiple sclerosis
Lodine XL (etodolac)
Treatment for arthritis
Lovenox (enoxaparin sodium) Injection
Treatment for prevention of blood clots following hip-replacement surgery
Lyrica (pregabalin)
For the treatment of neuropathic pain associated with spinal cord injury
Miacalcin (calcitonin-salmon) Nasal Spray
Treatment for post-menopausal osteoporosis
Mobic (meloxicam) Tablets
For relief of the signs and symptoms of osteoarthritis
Injectable solution for the treatment of abnormal head position and neck pain associated with cervical dystonia
Myrbetriq (mirabegron)
For the treatment of overactive bladder
Naglazyme (galsulfase)
For the treatment of mucopolysaccharidosis VI (Maroteaux-Lamy syndrome)
Naprelan (naproxen sodium)
Treatment for osteoarthritis and rheumatoid arthritis
Neupro (Rotigotine Transdermal System)
For the treatment of Restless Legs Syndrome
Orencia (abatacept)
For the treatment of Juvenile Idiopathic Arthritis
Otezla (apremilast)
For the treatment of adults with active psoriatic arthritis
OxyContin (oxycodone HCl controlled-release)
Treatment for pain associated with musculoskeletal conditions
Pennsaid (diclofenac sodium topical solution)
For the treatment of osteoarthritis of the knee
Plegridy (peginterferon beta-1a)
For the treatment of relapsing multiple sclerosis
Premarin (conjugated estrogens)
For the prevention of postmenopausal osteoporosis and treatment of vasomotor menopause symptoms
Prempro & Premphase (conjugated estrogens/medroxyprogesterone acetate tablets)
Treatment for postmenopausal hormone replacement, postmenopausal osteoporosis
Prolia (denosumab)
For the treatment of postmenopausal women with osteoporosis at high risk for fracture
Rayos (prednisone) delayed-release tablets
For the treatment of certain inflammatory diseases, including arthritis, COPD, asthma and psoriatic conditions
Reclast (zoledronic acid)
For the treatment of Paget's disease
Reclast (zoledronic acid)
For the treatment of postmenopausal osteoporosis
Remicade (infliximab)
Intravenous infusion for the treatment of rheumatoid arthritis
Sabril (vigabatrin)
For the treatment of infantile spasms and complex partial seizures
Treatment for growth hormone deficiency and Turner Syndrome
Savella (milnacipran hydrochloride)
For the treatment of fibromyalgia
Treatment for the reduction of scar tissue as a result of abdominal or pelvic surgery
Simponi (golimumab)
For the treatment of rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis
Skelid (tiludronate disodium)
Treatment for Paget’s disease of bone
Somatuline Depot (lanreotide acetate)
For the treatment of acromegaly
Somavert (pegvisomant)
Injectable formulation for the treatment of acromegaly
Stendra (avanafil)
For the treatment of erectile dysfunction
Joint fluid therapy for treatment of osteoarthritis in the knee
Synvisc, Synvisc-One (Hylan GF 20)
For the treatment of pain associated with osteoarthritis of the knee
Tecfidera (dimethyl fumarate)
For the treatment of relapsing multiple sclerosis
External cream for the treatment of male hormone deficiency.
Tolmetin Sodium
Treatment for arthritis
Velcade (bortezomib)
Injectable agent for the treatment of multiple myeloma patients who have received at least two prior therapies.
Vimizim (elosulfase alfa)
For the treatment of Mucopolysaccharidosis type IVA
Vimovo (naproxen + esomeprazole)
For the treatment of arthritis in patients at risk for NSAID-associated ulcers
Vioxx (rofecoxib)
For the treatment of rheumatoid arthritis
Vivelle-Dot (estradiol transdermal system)
For the prevention of post-menopausal osteoporosis
Vivlodex (meloxicam)
For the management of osteoarthritis pain
Votrient (pazopanib)
For the treatment of soft tissue sarcoma
Xeljanz (tofacitinib)
For the treatment of moderately to severely active rheumatoid arthritis
Xenazine (tetrabenazine)
For the treatment of chorea due to Huntington's disease
Xeomin (incobotulinumtoxinA)
For the treatment of cervical dystonia and blepharospasm
Xgeva (denosumab)
For the prevention of skeletal-related events in patients with bone metastases from solid tumors
Xiaflex (collagenase clostridium histolyticum)
For the treatment of Dupuytren’s contracture
Zanaflex (tizanidine hydrochloride)
Treatment for muscle spasticity
Zinbryta (daclizumab)
For the treatment of relapsing multiple sclerosis

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FDA Approved Musculoskeletal Drugs Listings:

The rules of principle for evaluating MediLexicon's FDA musculoskeletal drugs listings adhere to the FDA definitions of a new drug approval or a new molecular entity, and the Tufts Center for the Study of Drug Development.

MediLexicon's FDA Approved Drugs Listings include:

New Molecular Entities (NME): these NME's are described as a medication containing an active substance that have never previously approved in the US for marketing in any manner, shape or form (as defined by the FDA). In addition to this, there is also the inclusion of some FDA's Center for Drug Evaluation and Research (CDER) approved recombinant proteins and biologics.

MediLexicon's FDA Approved Drugs Listings do NOT include:

Over-the-counter products, diagnostic agents, generics, most vaccines, medical devices, biologic compounds (not approved by CDER), as well as new indications and new administrations of previously-approved compounds and new dosages.

The musculoskeletal drugs information used in this section is licensed from Thomson CenterWatch. The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.

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