Ethyol (amifostine)Company: U.S. Bioscience, Alza
Approval Status: Approved June 1999
Treatment for: Oncology
Areas: Diabetes / Endocrinology; Cancer & Oncology; ENT (Ear, Nose and Throat)
Possible similar drugs: Ethyol
Ethyol has been approved to reduce xerostomia in patients undergoing post-operative radiation treatment for head and neck cancer, where the radiation port includes a substantial portion of the parotid glands. Xerostomia--a chronic dry mouth condition--is a severe and often irreversible side effect of radiation therapy caused by damage to the salivary glands.
Side effects of Ethyol plus radiation in a Phase III study included nausea and vomiting which were sometimes severe. Side effects also included hypotension, fever, allergic-type skin reactions, dizziness/lightheadedness, fatigue/lethargy, rigors/chills, sneezing, sleepiness/somnolence, and flushing.
Ethyol Drug Information
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