MediLexicon Logo
MediLexicon Logo
Abbreviations        Abbrev Definitions        Dictionary        ICD9 Codes        Equipment        Hospitals        Drugs        More..
  

Useful Websites

Global Translations
Medical and Clinical Translation

specialistinfo.com
Details of over 40,000 UK Specialists and over 42,000 GPs

Global RPH
medical software

Doctors Lounge
Ask a Doctor and Disease Information

Health News
from Medical News Today.

MRCP 1 Revision
123 Doc medical courses for junior doctors.

CoreyNahman
pharmaceutical news daily

Hospital Search
Worldwide hospital database, search by country or keyword.

Metric Conversions
The Converter Site - unit conversion tool.
home > drug information > Migranal

Migranal


Company: Novartis
Approval Status: Approved December 1997
Treatment for: migraine
Areas: Neurology

| General Information | Clinical Results | Side Effects | Mechanism of Action |


General Information

Other Useful Resources

Migranal (dihydroergotamine mesylate, USP) has been approved for the acute treatment of migraine headaches with or without aura.



< back to top

Clinical Results

In clinical trials, self-administration of Migranal Nasal Spray resulted in significant pain relief and decreases in pain intensity and nausea compared with placebo. In the two most recent clinical trials, patients began to feel headache relief as early as 30 minutes after treatment with Migranal Nasal Spray. In those same trials, up to 60% of patients responded by two hours, and up to 70% responded by four hours, following a single 2 mg Migranal treatment. The majority of patients in all pivotal clinical trials did not need additional medications for their migraine headaches during the 24 hour period following a single 2 mg Migranal treatment.



< back to top

Side Effects

In clinical trials, side effects were usually mild and transient; the most common were rhinitis, altered sense of taste, dizziness, nausea, vomiting, and application site reaction.



< back to top

Mechanism of Action

Migranal Nasal Spray is a migraine-specific serotonin agonist that works at multiple receptor sites. Migranal Nasal Spray attacks migraine at its source by selectively binding to receptors in the brain that regulate the release of serotonin, a chemical considered to play a key role in the development of migraine.



< back to top



The FDA drug information shown here is licensed from Thomson CenterWatch. The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.




free web search box


pda medical dictionary
pda software - $15

PDA Medical Dictionary

only $15

Take MediLexicon's abbreviations search with you where-ever you go with our PDA software. As an extra, this software is available with an extra medical dictionary...

>> Click here for more on the PDA Medical Dictionary <<




add to google

Add our searches to your Google homepage.

Add to Google

The 60 seconds challenge: Add these searches to your Google homepage within 60 seconds - simply click here and follow these instructions


Receive the latest medical news on your Google homepage.

Add to Google

The 60 seconds challenge: Receive the latest medical news on your Google homepage within 60 seconds - simply click here and follow these instructions





Privacy Policy   |    Disclaimer      

MediLexicon International Ltd, UK Office: +44 (0) 1625 415 347
MediLexicon International Ltd © 2009 All rights reserved.