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Company: Braintree Laboratories
Approval Status: Approved April 2001
Treatment for: Hyperphosphetemia
Areas: Urology & Kidneys

| General Information | Clinical Results | Side Effects | Mechanism of Action | Additional Information |

General Information

PhosLo, in both capsule and gelcap formulations, has been approved for the control of hyperphosphatemia in end stage renal failure in adult patients. Patients suffering from kidney disease may experience increased blood levels of phosphate, which plays a pivotal role in causing secondary hyperpara-thyroidism associated with osteodystrophy and soft-tissue calcification. The rate of removal of phosphate by dialysis or by dietary manipulation is insufficient.

Clinical Results

Studies have confirmed that using calcium acetate as a phosphorus binder will control serum phosphorus levels in most dialysis outpatients.

Side Effects

Adverse events associated with the use of PhosLo capsules or gelcaps may include (but are not limited to) the following:

  • Nausea
  • Constipation
  • Vomiting
  • Stomach pains
  • Anorexia

Mechanism of Action

PhosLo (calcium acetate) binds to the phosphate taken in through one's diet to form insoluble calcium phosphate. This is then excreted from the body without being absorbed.

Additional Information

For additional information on PhosLo, please visit Braintree Laboratories.

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PhosLo Drug Information

The Phoslo drug information shown above is licensed from Thomson CenterWatch. The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.

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