Definition: 'Immune Complex Glomerulonephritis'
immune complex glomerulonephritisType: Term
1. immune complexes are deposited in the renal glomerulus where they bind complement and initiate an inflammatory process, attracting neutrophils and macrophages, resulting in an alteration of the basement layer of the kidney. The disease state can lead to ultimate destruction of the glomerulus and renal failure.
The definition information for immune complex glomerulonephritis is provided by Stedman's. You can search our medical dictionary here.