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Definition: 'Incretin'

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incretin

Type: Term

Pronunciation: in-krē′tin

Definitions:
1. Generic term for all insulinotropic substances originating in the gastrointestinal tract that are released into the circulation by meals containing glucose. One is glucose-dependent insulinotropic polypeptide, which is released into the circulation from crypt cells in the proximal duodenum and jejunum after meals containing glucose or long-chain fatty acids. Another is proglucagon-derived polypeptide, cleavage product of glucagon, which is further processed into glucagonlike peptide-1 and then to glucagonlike insulinotropic peptide.

The definition information for incretin is provided by Stedman's. You can search our medical dictionary here.

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Medical Dictionary Copyright © 2006 Lippincott Williams & Wilkins. All rights reserved.







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