Definition: 'Isotype Switch'
isotype switchType: Term
1. the process whereby the constant region gene of an antibody heavy chain is replaced with the constant region gene of another isotype, although the antigen-binding portion of the molecule is unchanged.
The definition information for isotype switch is provided by Stedman's. You can search our medical dictionary here.
Stedman's, part of Lippincott Williams & Wilkins, provides a comprehensive line of health-science publications for healthcare professionals and medical students.