Definition: '2-ketoadipic Acid Dehydrogenase Complex'

2-ketoadipic acid dehydrogenase complex

Definitions:
1. the multienzyme complex that reacts 2-ketoadipic acid with coenzyme A and NAD+ to produce glutaryl-CoA, CO₂, and NADH + H+ in l-lysine and l-tryptophan catabolism; a deficiency of one of the proteins in this complex results in 2-ketoadipic acidemia.

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