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Definition: 'Schick Test'

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Schick test

Type: Term

Pronunciation: shik

1. a test for susceptibility to Corynebacterium diphtheriae toxin: 0.1 mL of Schick test toxin is injected into the skin of one forearm (test site) and the same quantity of the same, but heat-inactivated, material into the skin of the other forearm (control site); those with toxin-neutralizing antibodies either will have no reaction at either injection site (negative test) or may have a pseudoreaction due to antibodies for substances (antigens) in the test materials other than diphtheria toxin; people lacking toxin-neutralizing antibodies may have a positive reaction, which consists of an area of redness appearing 24–36 hours at the test site only and persisting for 4–5 days.

Synonyms: Schick method

The definition information for Schick test is provided by Stedman's. You can search our medical dictionary here.

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