 Psoriasis: Scratching The SurfaceMain Category: Eczema / PsoriasisArticle Date: 16 Oct 2012 Psoriasis is a chronic inflammatory skin disorder that affects approximately 2% of the world's population. A group of inflammatory molecules known as interleukins activate an immune response that causes itchy skin, but it is unclear how the skin cells and immune cells communicate. In a study published in the Journal of Clinical Investigation, researchers led by Manfred Kopf at the Swiss Federal Institute of Technology in Zürich, Switzerland found that mice lacking interleukin-36 (IL-36) were protected from immune-mediated skin inflammation. These results indicate that IL-36 might be a useful therapeutic target in the treatment of psoriasis. TITLE: Psoriasiform dermatitis is driven by interleukin-36-mediated dendritic cell-keratinocyte crosstalk View this article at: http://www.jci.org/articles/view/63451?key=94c50375c771888cd255 Original article posted on Medical News Today. Articles not to be reproduced without permission of Medical News Today Medical News Today publishes the latest health news and health videos for consumers and health professionals. It has a searchable archive of over 100,000 health news articles. < back to medical news
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